EC Number   |
Protein Variants |
Reference |
|---|
    3.5.2.3 | C181A |
site-directed mutagenesis, the mutant shows reduced activity and altered kinetics compared to wild-type |
757192 |
| 3.5.2.3 | C181G |
site-directed mutagenesis, the mutant does not restore the activity of DHOase that has been isolated from aspartate transcarbamylase (ATCase, EC 2.1.3.2) |
756707 |
| 3.5.2.3 | C221S/C263S/C265S/C268S |
this quadruple mutant is relatively stable to oxidation and has kinetic parameters consistent with reported values for wild type DHO |
667912 |
| 3.5.2.3 | D179V |
site-directed mutagenesis, the mutant partially restores the activity of DHOase that has been isolated from aspartate transcarbamylase (ATCase, EC 2.1.3.2) |
756707 |
| 3.5.2.3 | D183G |
site-directed mutagenesis, the mutant partially restores the activity of DHOase that has been isolated from aspartate transcarbamylase (ATCase, EC 2.1.3.2) |
756707 |
| 3.5.2.3 | D230G |
catalytically inactive |
667738 |
| 3.5.2.3 | D230N |
catalytically inactive |
667738 |
| 3.5.2.3 | D250A |
less than 1% of the activity possessed by the wild type enzyme |
667595 |
| 3.5.2.3 | D250E |
reduced catalytic activity compared to wild type |
667595 |
| 3.5.2.3 | D250H |
less than 1% of the activity possessed by the wild type enzyme |
667595 |
