EC Number |
Protein Variants |
Reference |
---|
3.5.1.60 | A47V |
site-directed mutagenesis |
755270 |
3.5.1.60 | A75R |
site-directed mutagenesis |
755270 |
3.5.1.60 | C116A |
site-directed mutagenesis, inhibition of disulfide bridge formation |
755270 |
3.5.1.60 | H142R |
site-directed mutagenesis |
755270 |
3.5.1.60 | K95E |
site-directed mutagenesis |
755270 |
3.5.1.60 | L325A |
site-directed mutagenesis of isozyme A, the mutant shows reduced activity compared to wild-type |
752811 |
3.5.1.60 | L325T |
site-directed mutagenesis of isozyme A, the mutant shows reduced activity compared to wild-type |
752811 |
3.5.1.60 | more |
selective alkylation of the enzyme's cysteine residues results in almost complete loss of activity |
734562 |
3.5.1.60 | N112S |
site-directed mutagenesis, the mutation abolishes an N-linked glycosylation site |
755270 |
3.5.1.60 | N163D |
site-directed mutagenesis |
755270 |