EC Number   |
Protein Variants |
Reference |
|---|
   3.5.1.48 | D94A |
site-directed mutagenesis, steady-state kinetics |
754843 |
| 3.5.1.48 | E274L |
site-directed mutagenesis, steady-state kinetics, mutation of the glutamate gatekeeper residue |
754843 |
| 3.5.1.48 | H159A |
catalytically inactive mutant |
733494 |
| 3.5.1.48 | more |
construction of deletion mutant DELTAnuA2, steady-state kinetics. The universal 310 helix nuA2 insertion in loop L1 further constricts the HDAC10 active site. Generation of mutant zHDAC10DELTA by treatement with trypsin |
754843 |
| 3.5.1.48 | N93A |
site-directed mutagenesis, steady-state kinetics |
754843 |
| 3.5.1.48 | Y307F |
site-directed mutagenesis, introduction of the deactivating Y307F mutation facilitates crystallization |
754843 |
