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EC Number
Protein Variants
Commentary
Reference
3.5.1.135
D27A
the mutant shows severely reduced activity compared to the wild type enzyme
758354
3.5.1.135
E74A
with N4-acetylcytidine and N4-acetylcytosine, the turnover number of the mutant is 1000fold and 100fold lower, respectively, than that of the wild type enzyme
758354
3.5.1.135
H70A
more than 10fold decrease in activity towards N4-acetylcytidine and N4-acetylcytosine is observed for the mutant enzyme
758354
3.5.1.135
K21A
catalytically inactive
758354
3.5.1.135
R26A
catalytically inactive
758354
3.5.1.135
T24A
catalytically inactive
758354
3.5.1.135
Y89A
more than 3fold decrease in activity towards N4-acetylcytidine and N4-acetylcytosine is observed for the mutant enzyme
758354
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