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Protein Variants:
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EC Number
Protein Variants
Commentary
Reference
3.4.24.74
A394E
mutation does not affect BFT processing or secretion
668932
3.4.24.74
E349A
expression of BFT similar to that of wild type
668924
3.4.24.74
E349A
inactive
733837
,
734242
3.4.24.74
E349A
no activity with E-cadherin
734632
3.4.24.74
E349A
residual activity against fibrinogen and fluorophore-labeled casein
720923
3.4.24.74
G355R
expression of BFT similar to that of wild type
668924
3.4.24.74
H348D
smaller amounts of BFT compared to wild type
668924
3.4.24.74
H348Y/H352Y/H358Y
inactive
753653
3.4.24.74
H348Y/H352Y/H358Y
no activity with E-cadherin
734632
3.4.24.74
H352Y
Alexa-488-labeled BFT binding to HT29/C1 not blocked
-
,
668931
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