EC Number   |
Protein Variants |
Reference |
|---|
   3.4.24.61 | C948A |
the mutation of a highly conserved cysteine residue in NRD to Ala abolishes the potentiation by tubulin |
719245 |
| 3.4.24.61 | DELTA1-148 |
mutant does not bind the H3K4me2 peptide |
720003 |
| 3.4.24.61 | DELTA1-260 |
mutant binds the H3K4me2 peptide |
720003 |
| 3.4.24.61 | DELTA1-445 |
mutant binds the H3K4me2 peptide |
720003 |
| 3.4.24.61 | DELTA1-621 |
mutant binds the H3K4me2 peptide |
720003 |
| 3.4.24.61 | DELTA149-621 |
mutant does not bind the H3K4me2 peptide |
720003 |
| 3.4.24.61 | E235A |
inactive mutant |
683128, 683793 |
| 3.4.24.61 | more |
detection and reconstruction of the naturally occurring mutation APP770, overview |
683793 |
| 3.4.24.61 | more |
enzyme-GFP fusion construct, 90-95% of protein is cytoplasmic, 3-6% of protein is nuclear. Nuclear localization signal mutant and N-terminally truncated enzyme-GFP construct, completely cytoplasmic localization. After treatment with leptomycin B or spermidine, increase in nuclear localization of enzyme-GFP fusion protein |
667300 |
| 3.4.24.61 | more |
nardilysin null mice have smaller brains and a thin cerebral cortex, in which are less myelinated fibers with thinner myelin sheaths and smaller axon diameters, compared to wild-type mice. The mutants show hypomyelination in the peripheral nervous system, phenotype, overview. Neuron-specific overexpression of nardilysin induces hypermyelination |
710043 |
