EC Number   |
Protein Variants |
Reference |
|---|
   3.4.24.22 | down |
aldose reductase inhibitor, fidarestat, normalizes high-glucose level-mediated suppression of MMP-10 expression, it downregulates MMP-10 expression |
708292 |
| 3.4.24.22 | medicine |
cells resistant to protein kinase C potentiated, transcription factor p53 mediated apoptosis express a higher level of matrix metalloproteinases MMP-9 and MMP-10. Matrix metalloproteinases function confers protection from protein kinase C/p53 induced apoptosis and are implicated in tumor cell resistance |
668151 |
| 3.4.24.22 | more |
generation of Mmp10-/- knockout mice |
753928 |
| 3.4.24.22 | more |
mice injected with lymphoma cells constitutively expressing enzyme developed thymic lymphoma more rapidly than those injected with control lymphoma cells |
669712 |
| 3.4.24.22 | more |
MMP-10 knockdown by siRNA |
709245 |
| 3.4.24.22 | more |
stromelysin-2 deficiency does not affect adipose tissue formation in a mouse model of nutritionally induced obesity, no effect on total body weight or on subcutaneous adipose tissue mass of mice kept on a high fat diet for 15 weeks, while or gonadal adipose tissue development is reduced, phenotype, overview. Significantly reduced MMP-3 expression in MMP-10-deficient adipose tissues not affecting blood vessel size |
707379 |
| 3.4.24.22 | up |
a high glucose level decreases MMP-10 expression in corneal epithelial cells |
708292 |
| 3.4.24.22 | V94G |
constitutively active mutant, mice expressing the mutant in keratinocytes have no alterations in skin architecture, and the healing rate of skin wounds is normal. Histologically, deposition of new matrix is reduced and keratinocytes at the migrating epidermal tip are scattered, the staining pattern of laminin-5 at the wound site is altered |
670198 |
