EC Number |
Protein Variants |
Reference |
---|
3.4.21.97 | A133V |
I-site mutant |
95603 |
3.4.21.97 | A134Q |
oligomerization at high protein concentration |
95600 |
3.4.21.97 | A143Q |
all enzyme samples used in this experiments contain an additional mutation, A143Q. The mutation disables one of the internal cleavage sites but has little effects on the kinetic properties of the enzyme |
653320 |
3.4.21.97 | A143Q/D217N |
the ratio of turnover number to Km-value is 11% of that for mutant enzyme A143Q |
653320 |
3.4.21.97 | A143Q/D227N |
the ratio of turnover number to Km-value is 1273fold lower than that for mutant A143Q |
653320 |
3.4.21.97 | A143Q/E31R |
the ratio of turnover number to Km-value is 44.6fold lower than that for the wild-typelike mutant A143Q |
650227 |
3.4.21.97 | A143Q/E31S |
the ratio of turnover number to Km-value is 4.8fold lower than that for the wild-typelike mutant A143Q |
650227 |
3.4.21.97 | A143Q/H157A |
the ratio of turnover number to Km-value is 22fold lower than that of the wild-typelike mutant enzyme A143Q |
650071 |
3.4.21.97 | A143Q/H157E |
the ratio of turnover number to Km-value is 11.7fold lower than that of the wild-typelike mutant enzyme A143Q |
650071 |
3.4.21.97 | A143Q/H157Q |
the ratio of turnover number to Km-value is 19fold lower than that of the wild-typelike mutant enzyme A143Q |
650071 |