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Results 1 - 10 of 28 > >>
EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46C25A has increased activity compared to the native VEGF-DDELTANDELTAC. Efficiently binds to the soluble receptor VEGFR-2/IgGFc. The C25A mutant behaves mainly as a monomeric protein on SDS-PAGE under reducing conditions but as a dimeric protein under non-reducing conditions. It induces VEGFR-2 Tyr-1175 phosphorylation 698902
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46C25A/P43S has biological activity comparable to that of the native protein in Ba/F3-VEGFR-2 cells 698902
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46C25I is mainly in a presumably covalently bound dimeric form 698902
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46C25L has increased activity compared to the native VEGF-DDELTANDELTAC, the C25L mutant is the most active mutant and is mainly in a presumably covalently bound dimeric form, has highest affinity to bind soluble receptor VEGFR-2/IgGFc. It induces VEGFR-2 Tyr-1175 phosphorylation 698902
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46C25V is mainly in a presumably covalently bound dimeric form 698902
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46C44A does not bind to the soluble receptor VEGFR-2/IgGFc 698902
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46C53A does not bind the soluble receptors VEGFR-2/IgGFc and VEGFR-3/IgGFc 698902
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46C53A does not bind to the soluble receptor VEGFR-2/IgGFc 698902
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46G51C can not induce cell survival, has increased dimer to monomer ratio 698902
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46H133A catalytically inactive 718398
Results 1 - 10 of 28 > >>