EC Number   |
Protein Variants |
Reference |
|---|
   3.4.21.112 | E75A/E76A |
is catalytically inactive and traps RsiW in a complex in which the anti-sigma factor is protected from undergoing proteolysis |
-, 686949 |
| 3.4.21.112 | E95K |
missense mutant with a a dominant (gain-of-function) mutation. Exhibits heightened resistance to the SdpC toxin in cells lacking the SdpI immunity protein. Is locked in a state that causes constitutive activation of sigmaW |
-, 686949 |
| 3.4.21.112 | H175A |
is catalytically inactive and traps RsiW in a complex in which the anti-sigma factor is protected from undergoing proteolysis |
-, 686949 |
| 3.4.21.112 | H249A |
active site mutant, autocatalytic generation of St-1 is abrogated, St-2 fragment is generated at a level of ca. 15% |
687607 |
| 3.4.21.112 | H249A |
site-directed mutagenesis, catalytically inactive mutant |
732162 |
| 3.4.21.112 | H249A |
site-directed mutagenesis, catalytically inactive mutant showing no autoprocessing |
732421 |
| 3.4.21.112 | I985A |
has no effect on generation of St-2 |
687607 |
| 3.4.21.112 | I989L |
results in more than 90% reduction in the generation of St-2 |
687607 |
| 3.4.21.112 | K948A |
shedding site mutant |
687607 |
| 3.4.21.112 | L952A |
shedding site mutant |
687607 |
