EC Number   |
Protein Variants |
Reference |
|---|
   3.4.19.13 | DELTAY385-E398 |
no autocatalytic processing, no catalytic activity |
731359 |
| 3.4.19.13 | DELTAY385-I387 |
mutant is able to autoprocess itself, leading to the formation of a small and a large subunit with masses of about 41 kDa and 22 kDa, respectively. Mutant shows increase in catalytic efficiency |
731359 |
| 3.4.19.13 | DELTAY385-I396 |
mutant is able to autoprocess itself, albeit slowly, leading to the formation of a small and a large subunit with masses of about 41 kDa and 22 kDa, respectively. Mutant shows decrease in catalytic efficiency |
731359 |
| 3.4.19.13 | DELTAY385-K394 |
mutant is able to autoprocess itself, albeit slowly, leading to the formation of a small and a large subunit with masses of about 41 kDa and 22 kDa, respectively. Mutant shows decrease in catalytic efficiency |
731359 |
| 3.4.19.13 | DELTAY385-P391 |
mutant is able to autoprocess itself, albeit slowly, leading to the formation of a small and a large subunit with masses of about 41 kDa and 22 kDa, respectively. Mutant shows decrease in catalytic efficiency |
731359 |
| 3.4.19.13 | DELTAY385-V388 |
mutant is able to autoprocess itself, leading to the formation of a small and a large subunit with masses of about 41 kDa and 22 kDa, respectively. Mutant shows increase in catalytic efficiency |
731359 |
| 3.4.19.13 | T391A |
processing-deficient mutant protein, molecular mass of 100000 Da |
722626 |
| 3.4.19.13 | T391A |
unable to undergo autocatalytic processing, crystallization data |
676861 |
| 3.4.19.13 | T398A |
mutation results in an enzyme that is fully capable of autoprocessing but is devoid of enzymatic activity |
722656 |
| 3.4.19.13 | T398S |
retains considerable enzymatic activity, but hydrolysis rates are reduced about 5fold relative to wild-type enzyme and overall catalyticefficiency is diminished by nearly an order of magnitude |
722656 |
