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EC Number
Protein Variants
Commentary
Reference
3.2.2.B5
D166N
mutant enzyme shows wild-type activity
726058
3.2.2.B5
D172N
binds to 8-oxoguanine containing single-stranded DNA more tightly than double-stranded DNA containing a 8-oxoguanine/cytosine base pair
724823
3.2.2.B5
D172N
inactive mutant enzyme
-
,
726058
3.2.2.B5
D172Q
binds to 8-oxoguanine containing single-stranded DNA more tightly than double-stranded DNA containing a 8-oxoguanine/cytosine base pair
724823
3.2.2.B5
D172Q
no detectable glycosylase activity
724823
3.2.2.B5
K128Q
glycosylase-deficient mutant
-
,
726497
3.2.2.B5
K129S
inactive mutant enzyme
-
,
725337
3.2.2.B5
K140Q
binds to 8-oxoguanine containing single-stranded DNA more tightly than double-stranded DNA containing a 8-oxoguanine/cytosine base pair
724823
3.2.2.B5
K140Q
inactive mutant enzyme
726058
3.2.2.B5
K147Q
activity of mutant enzyme is severely attenuated
726058
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