EC Number   |
Protein Variants |
Reference |
|---|
   3.2.2.3 | H254A |
sited-directed mutagenesis, active site mutant, 30fold decreased Vmax and unaltered Km compared to the wild-type enzyme |
655283 |
| 3.2.2.3 | more |
construction of urh115 disruption mutant strains |
655283 |
| 3.2.2.3 | more |
expression of uridine-cytidine N-ribohydrolase from protozoan parasite Crithidia fasciculata in a Saccharomyces mutant deficient restores the enzyme activity, as well as expression of the human enzyme in the yeast mutant |
638539 |
| 3.2.2.3 | more |
functional knockout of the mutant, phenotypic analysis of wild-type and mutant enzymes, overview |
732656 |
| 3.2.2.3 | more |
mutants expressing the Arabidopsis thaliana enzyme or the homologue from Oryza sativa exhibit resistance toward toxic fluorouridine, fluorouracil, and fluoroorotic acid. Mutants with increased and decreased nucleosidase activity are delayed in germination |
700741 |
