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EC Number	Protein Variants	Commentary	Reference
3.2.2.16	A113P	the mutant shows reduced catalytic efficiency compared to the wild type enzyme	727044
3.2.2.16	A113P/V153I	the mutant shows reduced catalytic efficiency compared to the wild type enzyme	727044
3.2.2.16	A113P/V153I/R158G	the mutant shows reduced catalytic efficiency compared to the wild type enzyme	727044
3.2.2.16	A15M	the mutant exhibits less than 16% catalytic efficiency compared to the wild type	726889
3.2.2.16	D168A	inactive	726889
3.2.2.16	D168N	inactive	726889
3.2.2.16	D198N	inactive	727008
3.2.2.16	D199A	site-directed mutagenesis, structure determination and comparison to the wild-type enzyme	726595
3.2.2.16	D199A	the enzyme shows minor activity towards 6-amino-6-deoxyfutalosine	726595
3.2.2.16	D199N	inactive	726595

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Release 2023.1 (January 2023)