EC Number |
Protein Variants |
Reference |
---|
3.1.7.2 | D81A |
loss of hydrolytic activity with retention of synthesis |
661218 |
3.1.7.2 | DElTA1-86/DELTA395-738 |
contains only (p)ppGpp synthesis activity, no hydrolysis activity |
661218 |
3.1.7.2 | DELTA182-738 |
fragment contains only (p)ppGpp hydrolysis activity, no synthesis activity |
661218 |
3.1.7.2 | DELTA395-738 |
frament contains both synthesis and hydrolysis activities |
661218 |
3.1.7.2 | E319Q |
mutant lacks (p)ppGpp synthase activity but retains hydrolase activity |
750643 |
3.1.7.2 | G241E |
loss of synthetic activity and retention of hydrolysis |
661218 |
3.1.7.2 | H344Y |
loss of synthetic activity and retention of hydrolysis |
661218 |
3.1.7.2 | H80A |
loss of hydrolytic activity with retention of synthesis |
661218 |
3.1.7.2 | more |
diverse deletion mutants show synthesis and degradation activities differing from those of full-length enzyme |
-, 651696 |
3.1.7.2 | more |
Mesh1 deletion by imprecise excision of a P-element from the Drosophila Mesh1 G3858 allele, resulting in the Drosophila Mesh1 null allele, Mesh1 5A3. The Mesh1 null mutant is much more susceptible than wild-type flies to death from amino acid starvation, and this susceptibility is also completely rescued by Mesh1 expression |
716313 |