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EC Number
Protein Variants
Commentary
Reference
3.1.4.50
H125N
inactive mutant enzyme
663968
3.1.4.50
H133N
inactive mutant enzyme
663968
3.1.4.50
H158N
inactive mutant enzyme
663968
3.1.4.50
H29N
inactive mutant enzyme
663968
3.1.4.50
H56N
inactive mutant enzyme
663968
3.1.4.50
H88N
inactive mutant enzyme
663968
3.1.4.50
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C-terminal deletion of 2-5 amino acids results in loss of about 70% of enzymic activity, deletion of more than 5 amino acids results in complete loss of activity, Y811 may be crucial for activity
646490
3.1.4.50
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signal-peptide deficient form of enzyme is catalytically active and intracellularly localized, GPI-anchored form of enzyme is catalytically active and cells release endogenous GPI-anchored alkaline phosphatase
646481
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