EC Number   |
Protein Variants |
Reference |
|---|
    3.1.3.3 | D15A/E33A |
the mutant shows reduced activity compared to the wild type enzyme |
749921 |
| 3.1.3.3 | D185G |
complete loss of activity |
-, 730055 |
| 3.1.3.3 | D198N |
9% activity of the wild type enzyme |
682506 |
| 3.1.3.3 | D341G |
about 10% residual activity, no change in secondary structure compared to wild-type |
-, 730055 |
| 3.1.3.3 | delI211 |
50fold decrease in catalytic efficiency |
-, 730011 |
| 3.1.3.3 | delVal2-I211 |
400fold decrease in catalytic efficiency |
-, 730011 |
| 3.1.3.3 | E29D |
less than 5% of the activity of wild-type enzyme with L-phosphoserine as substrate |
652336 |
| 3.1.3.3 | E29Q |
inactive mutant enzyme |
652336 |
| 3.1.3.3 | G18A/G108A |
the mutant shows reduced activity compared to the wild type enzyme |
749921 |
| 3.1.3.3 | H85A |
almost complete loss of activity |
-, 730011 |
