EC Number   |
Protein Variants |
Reference |
|---|
   3.1.13.4 | A519V |
site-directed mutagenesis of Pab1p, the mutant shows no resistance to 3-AT in contrast to the wild-type protein, identification of interaction residues and domains with Ppb1p, Pan2p and Pan3p |
666343 |
| 3.1.13.4 | D28A |
catalytically inactive, RNA-binding is not affected |
652348 |
| 3.1.13.4 | D28A |
site-directed mutagenesis, catalytically inactive mutant, phenotype, overview |
751740 |
| 3.1.13.4 | D28A |
site-directed mutagenesis, structure comparison to the wild-type enzyme, the mutant shows unaltered ellipticity |
715205 |
| 3.1.13.4 | D28C |
mutants inactive in presence of Mg2+, but with restored activity in presence of soft divalent metal ions, amino acid interacts with catalytically essential metal ions |
-, 669291 |
| 3.1.13.4 | D292A |
catalytically inactive, RNA-binding is not affected |
652348 |
| 3.1.13.4 | D292A |
site-directed mutagenesis, structure comparison to the wild-type enzyme, the mutant shows unaltered ellipticity |
715205 |
| 3.1.13.4 | D292C |
mutants inactive in presence of Mg2+, but with restored activity in presence of soft divalent metal ions, amino acid interacts with catalytically essential metal ions |
-, 669291 |
| 3.1.13.4 | D382A |
catalytically inactive, RNA-binding is not affected |
652348 |
| 3.1.13.4 | D382A |
site-directed mutagenesis, structure comparison to the wild-type enzyme, the mutant shows slightly decreased ellipticity |
715205 |
