EC Number   |
Protein Variants |
Reference |
|---|
   2.8.1.4 | C265A |
cells expressing the C265A variant show 88% decrease in their 4-thiouridine level. The mutant enzyme contains no detectable amount of persulfide |
725494 |
| 2.8.1.4 | C268A |
cells expressing the C265A variant contain no 4-thiouridine. The mutant enzyme contains no detectable amount of persulfide |
725494 |
| 2.8.1.4 | C348A |
cells expressing the C348A variant show 33% decreases in their 4-thiouridine levels. The mutant enzyme contains no detectable amount of persulfide |
725494 |
| 2.8.1.4 | C78A |
cells expressing the C78A variant show 8% decrease in their 4-thiouridine levels. The C78A variant has similar amounts of persulfide as the wild-type protein |
725494 |
| 2.8.1.4 | more |
Ctu1 (cytosolic tRNA thiouridilase) associates with the conserved Ctu2 protein and this complex is the wobble uridine-34 thiolase of cytosolic tRNAs in eukaryotes, the complex is essential to maintaining genome stability |
694891 |
| 2.8.1.4 | more |
Ctu1 (cytosolic tRNA thiouridylase) associates with the conserved Ctu2 protein and this complex is the wobble uridine-34 thiolase of cytosolic tRNAs in eukaryotes, the complex is essential to maintaining genome stability |
694891 |
| 2.8.1.4 | more |
single or double deletion mutants of the fission yeast ctu1 and ctu2 genes results in a thermosensitive lethal phenotype reminiscent of the inactivation of their worm counterparts |
694891 |
