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Results 1 - 10 of 83 > >>
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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.88F1269A inactive 762033
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.88F1269A residue is essential or important for the PRNTase activity in the step of the covalent L-pRNA intermediate formation, but not for the GTPase activity that generates GDP. Mutant induces termination of mRNA synthesis at position +40 followed by aberrant stop-start transcription, and abolishes virus gene expression in host cells 739202
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.88F1269A site-directed mutagenesis, inactive mutant 762033
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.88F1269W site-directed mutagenesis, plaque phenotype compared to wild-type enzyme, the mutant shows 18% activity compared to wild-type 762033
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.88F1269W the mutant shows 18% activity compared to the wild type enzyme 762033
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.88F1269Y site-directed mutagenesis, plaque phenotype compared to wild-type enzyme, the mutant shows 31% activity compared to wild-type 762033
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.88F1269Y the mutant shows 31% activity compared to the wild type enzyme 762033
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.88F1285A mutation abolishes RNA capping activity 739751
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.88G1100A residue is essential or important for the PRNTase activity in the step of the covalent L-pRNA intermediate formation, but not for the GTPase activity that generates GDP. Mutant induces termination of mRNA synthesis at position +40 followed by aberrant stop-start transcription, and abolishes virus gene expression in host cells 739202
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.88G1100A site-directed mutagenesis, the mutant shows 11% activity compared to wild-type -, 762033
Results 1 - 10 of 83 > >>
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