EC Number   |
Protein Variants |
Reference |
|---|
    2.7.7.3 | F8L |
the enzyme mutant is less sensitive to inhibition by compound D compared to the wild-type enzyme |
737460 |
| 2.7.7.3 | I4V/N76Y |
the mutant is a homotetramer. Despite structural differences between wild type enzyme and IV4/N76Y, they have similar ligand-binding properties |
722832 |
| 2.7.7.3 | N106H |
the enzyme mutant is less sensitive to inhibition by compound D compared to the wild-type enzyme |
-, 737460 |
| 2.7.7.3 | N106Y |
the enzyme mutant is less sensitive to inhibition by compound D compared to the wild-type enzyme |
-, 737460 |
| 2.7.7.3 | N107H |
the enzyme mutant is less sensitive to inhibition by compound D compared to the wild-type enzyme |
737460 |
| 2.7.7.3 | R106A |
pantothenate kinase (PanK) mutant |
674344 |
| 2.7.7.3 | R90A/D94A |
in silico mutation, ligand acetyl-CoA fails to maintain its position inside the binding cavity |
-, 761731 |
| 2.7.7.3 | T117N |
the enzyme mutant is less sensitive to inhibition by compound D compared to the wild-type enzyme |
737460 |
| 2.7.7.3 | V136F |
the enzyme mutant is less sensitive to inhibition by compound D compared to the wild-type enzyme |
-, 737460 |
