EC Number |
Protein Variants |
Reference |
---|
2.7.11.9 | I439A/W588A |
site-directed mutagenesis, the mutant shows reduced binding of serum amyloid P |
722751 |
2.7.11.9 | more |
construction of antisense oligonucleotide-mediated loss-of-function and synthetic mRNA-based gain-of-function mutants. The loss-of-function phenotype is linked to cell death, evident primarily in the muscle of the somites, extensive loss of myelinated tracks, and brain edema, phenotype, overview |
693093 |
2.7.11.9 | more |
gpbp-1-/- mice and Tg-hGPBP-1 animals do not display any obvious morphological phenotype, gpbp-1-/- mice also do not show a functional phenotype, whereas Tg-hGPBP-1 mice display reduced endurance that is not attributable to mitochondrial alterations |
722724 |
2.7.11.9 | more |
immobilization of Goodpasture antigen-binding protein by human serum amyloid P component binding from solution and in plasma, overview. Serum amyloid P associates in the blood with a 37-kDa GPBP fragment containing the N-terminal region and the middle domain |
722751 |
2.7.11.9 | N460A/Y461A |
site-directed mutagenesis, the mutant shows unaltered binding of serum amyloid P |
722751 |
2.7.11.9 | P500G/A501Q |
site-directed mutagenesis, the mutant binding to serum amyloid P is abolished |
722751 |
2.7.11.9 | V498A/W499A |
site-directed mutagenesis, the mutant shows unaltered binding of serum amyloid P |
722751 |
2.7.11.9 | Y461A/F462A |
site-directed mutagenesis, the mutant shows reduced binding of serum amyloid P |
722751 |