EC Number   |
Protein Variants |
Reference |
|---|
   2.7.11.5 | D403A |
site-directed mutagenesis |
-, 640610 |
| 2.7.11.5 | D475A |
site-directed mutagenesis, the mutant shows completely reduced activity compared to the wild-type enzyme |
-, 723265 |
| 2.7.11.5 | D475A |
the mutation in this signature motif completely abolishes kinase activity of the enzyme |
723346 |
| 2.7.11.5 | D477A |
site-directed mutagenesis, the mutant shows only slightly reduced activity compared to the wild-type enzyme |
-, 723265 |
| 2.7.11.5 | E439A |
site-directed mutagenesis |
-, 640610 |
| 2.7.11.5 | E478A |
site-directed mutagenesis, the mutant shows slightly increased activity compared to the wild-type enzyme |
723265 |
| 2.7.11.5 | E497K/E499K |
site-directed mutagenesis, the mutant shows about 75% reduced activity compared to the wild-type enzyme |
723265 |
| 2.7.11.5 | K291A |
site-directed mutagenesis, the mutant shows unaltered activity compared to the wild-type enzyme |
-, 723265 |
| 2.7.11.5 | K336A |
site-directed mutagenesis, the mutant shows completely reduced activity compared to the wild-type enzyme |
-, 723265 |
| 2.7.11.5 | K346E |
site-directed mutagenesis, the mutant shows only slightly reduced activity compared to the wild-type enzyme |
723265 |
