EC Number |
Protein Variants |
Reference |
---|
2.7.11.23 | D167N |
dominant-negative mutant of CDK9, inhibits transcriptional activation by EBNA 2 |
682208 |
2.7.11.23 | D173A |
CDK8 mutant, shows no effect on basal or EBNA 2-activated transcription |
682208 |
2.7.11.23 | D324N |
inactive Ctk1 mutant |
661832 |
2.7.11.23 | D324N |
with catalytically dead allele of CTK1 |
-, 681926 |
2.7.11.23 | K41M |
CDK7 mutant, both EBNA 2-activated and basal transcription from Cp reporter construct are not particularly dependent on CDK7 kinase activity with only small effects observed in the presence of high levels of mutant K41M |
682208 |
2.7.11.23 | K85A |
kinase-dead mutant of isoform GSK-3beta |
762057 |
2.7.11.23 | more |
a temperature-sensitive mutant and the analog-sensitive mutant of Kin28 is that upon heat inactivation, Kin28ts alleles are unable to retain protein interactions with other subunits of the TFIIH complex |
689778 |
2.7.11.23 | more |
construction of an enzyme-deficient ctk1DELTA mutant strain which shows selective abolishment of histone H3 Lys36 methylation |
-, 661828 |
2.7.11.23 | more |
construction of ctk-disruption mutant strains displaying defects in nucleolar structure, the RNA polymerase I functions less effective in the mutant cells, the in vitro transcription is impaired |
662973 |
2.7.11.23 | more |
construction of several enzyme-deficient disruption mutant strains, overview, CTK1 can rescue the growth defects of an Ess1-deficient mutant at low concentration, but enhances the defects if overexpressed |
661832 |