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Results 1 - 10 of 39 > >>
EC Number Protein Variants Commentary Reference
Show all pathways known for 2.5.1.9Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.9A43L decrease in affinity for substrate 6,7-dimethyl-8-ribityllumazine. A43L replacement causes substantial perturbation of the overall binding site topology 687468
Show all pathways known for 2.5.1.9Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.9C48A site-directed mutagenesis, nearly inactive mutant 658346
Show all pathways known for 2.5.1.9Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.9C48M site-directed mutagenesis, nearly inactive mutant 658346
Show all pathways known for 2.5.1.9Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.9C48S mutation in the activity cavity, causes significant 19F NMR chemical shift modulation of trifluoromethyl derivatives of 6,7-dimethyl-8-ribityllumazine in complex with the protein. Replacement of C48 changes the electron density topology in the N-terminal substrate binding site in the vicinity of C-6 and C-7 atoms of bound ligand 687468
Show all pathways known for 2.5.1.9Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.9C48S site-directed mutagenesis, highly decreased activity compared to the wild-type enzyme 658346
Show all pathways known for 2.5.1.9Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.9D143G site-directed mutagenesis, soluble protein, too unstable to be purified 637580
Show all pathways known for 2.5.1.9Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.9D143N site-directed mutagenesis, soluble protein, too unstable to be purified 637580
Show all pathways known for 2.5.1.9Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.9D185L site-directed mutagenesis, low remaining activity 637580
Show all pathways known for 2.5.1.9Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.9DELTA1-180 variant that lacks the C-terminal extension the coiled-coil and C-terminal peptide (AaRS1-180) 759481
Show all pathways known for 2.5.1.9Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.9DELTA1-196 variant that lacks the C-terminal extension (1-196). Substantial decrease in association efficiency with lumazine synthase is observed for the truncated variant 759481
Results 1 - 10 of 39 > >>