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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.75D153A at least 25% of wild-type activity 696197
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.75D164A increase in Km for both substrates 696197
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.75D42A 20fold decrease in kcat 696197
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.75D55G site-directed mutagenesis, the mutant shows 50% reduced specific activity compared to the wild-type enzyme 737635
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.75E173A at least 25% of wild-type activity 696197
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.75E229A substantial increase in Km for RNA, dimethylallyl diphosphate becomes inhibitory at higher concentrations 696197
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.75F84A at least 25% of wild-type activity 696197
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.75H67F 25fold increase in Km for dimethylallyl diphosphate 696197
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.75K127D activity similar to wild-type 723760
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.75K181H selective disproportionate decrease in activity toward several substrates 723760
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