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EC Number	Protein Variants	Commentary	Reference
2.4.2.45	A35E	the mutant is associated with high-level ethambutol resistance and increases decaprenylphosphoryl-beta-D-arabinose levels	739151
2.4.2.45	A66F	inactive	720386
2.4.2.45	D74A	inactive	720386
2.4.2.45	D77A	inactive	720386
2.4.2.45	D77E	15% activity compared to the wild type enzyme	720386
2.4.2.45	D81A	inactive	720386
2.4.2.45	E195A	17% activity compared to the wild type enzyme	720386
2.4.2.45	F176L	the mutation is associated with ethambutol resistance	-, 739737
2.4.2.45	F59A	94% activity compared to the wild type enzyme	720386
2.4.2.45	F62A	72% activity compared to the wild type enzyme	720386

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Release 2023.1 (January 2023)