EC Number |
Protein Variants |
Reference |
---|
2.4.2.26 | C257A |
2.3fold decrease in the ratio of Vmax to KM-value as compared to wild-type enzyme |
657858 |
2.4.2.26 | C276A |
mutation results in a nearly inactive enzyme |
678024 |
2.4.2.26 | C285A |
5.4fold decrease in the ratio of Vmax to KM-value as compared to wild-type enzyme |
657858 |
2.4.2.26 | C301A |
2.3fold decrease in the ratio of Vmax to KM-value as compared to wild-type enzyme |
657858 |
2.4.2.26 | C471A |
complete loss of catalytic activity. N-phenylmaleimide treatment shows no effect on wild-type XT-I but strongly inactivates the cysteine mutant |
657858 |
2.4.2.26 | C542A |
2.9fold decrease in the ratio of Vmax to KM-value as compared to wild-type enzyme |
657858 |
2.4.2.26 | C561A |
UDP inhibition is significantly reduced |
657858 |
2.4.2.26 | C563A |
2fold decrease in the ratio of Vmax to KM-value as compared to wild-type enzyme |
657858 |
2.4.2.26 | C574A |
complete loss of catalytic activity. N-phenylmaleimide treatment shows no effect on wild-type XT-I but strongly inactivates the cysteine mutant |
657858 |
2.4.2.26 | C675A |
1.5fold increase in the ratio of Vmax to KM-value as compared to wild-type enzyme |
657858 |