2.4.1.244 | more |
B4GALNT3 overexpression enhances colon cancer cell malignant phenotypes in vitro and in vivo. Knockdown of B4GALNT3 using small interfering (si) RNAs in colon cancer cell lines (HCT116, SW480, HCT15, and HT29 cells) decrease sphere formation and the expression of stem cell markers, OCT4 and. NANOG. B4GALNT3 knockdown suppresses EGF-induced phosphorylation of epithelial growth factor receptor, EGFR, and its downstream signaling molecules |
736917 |