EC Number |
Protein Variants |
Reference |
---|
2.4.1.218 | A204V |
site-directed mutagenesis, mutant shows slightly reduced activity compared to the wild-type enzyme |
658631 |
2.4.1.218 | E368A |
site-directed mutagenesis, mutant shows reduced activity compared to the wild-type enzyme |
658631 |
2.4.1.218 | E368D |
site-directed mutagenesis, mutant shows reduced activity compared to the wild-type enzyme |
658631 |
2.4.1.218 | H360E |
site-directed mutagenesis, mutant shows about 4000fold reduced activity compared to the wild-type enzyme |
658631 |
2.4.1.218 | H360K |
site-directed mutagenesis, mutant shows about 1000fold reduced activity compared to the wild-type enzyme |
658631 |
2.4.1.218 | H360R |
site-directed mutagenesis, mutant shows about 1000fold reduced activity compared to the wild-type enzyme |
658631 |
2.4.1.218 | L86I |
site-directed mutagenesis, mutant shows slightly reduced activity compared to the wild-type enzyme |
658631 |
2.4.1.218 | more |
generation of the typical E-E motif of the enzyme does not convert a NRD1beta enzyme into a NRD1alpha enzyme |
658631 |