EC Number   |
Protein Variants |
Reference |
|---|
   2.3.2.23 | A157C |
a naturally occuring mutation involved in the Fanconi anaemia syndrome |
758749 |
| 2.3.2.23 | C105S/C146S |
mutation of the residues forming an intramolecular disulfide bond. Mutation does not disturb the secondary structure of the protein but does reduce the in vitro activity of isoform Pex4 |
735257 |
| 2.3.2.23 | C136F |
mutation results in constitutive binding of UbcM2 to transcription factor Nrf2 and an increased half-life of the transcription factor in vivo |
715517 |
| 2.3.2.23 | C93S |
sumoylatzion-defective mutant |
734157 |
| 2.3.2.23 | C94S |
site-directed mutagenesis, a catalytically inactive mutant |
758713 |
| 2.3.2.23 | D102K |
site-directed mutagenesis, analysis of ubiquitin specificity and reaction kinetics compared to wild-type |
759768 |
| 2.3.2.23 | D103K |
site-directed mutagenesis, analysis of ubiquitin specificity and reaction kinetics compared to wild-type |
759768 |
| 2.3.2.23 | D127G |
site-directed mutagenesis |
760168 |
| 2.3.2.23 | D143A |
site-directed mutagenesis, analysis of ubiquitin specificity and reaction kinetics compared to wild-type |
759768 |
| 2.3.2.23 | D143K |
site-directed mutagenesis, analysis of ubiquitin specificity and reaction kinetics compared to wild-type |
759768 |
