EC Number |
Protein Variants |
Reference |
---|
2.3.1.65 | BAAT-12AA Trunc |
mutant enzyme BAAT-12AA Trunc with 12 removed carboxy-terminal amino acids (407-418) |
757369 |
2.3.1.65 | BAAT-Ex1Del |
the amino (N)-terminal truncated mutant enzyme BAAT-Ex1Del possess no detectable N-acyltransferase activity |
757369 |
2.3.1.65 | BAAT-S |
the mutant BAAT-S, lacking the final two amino acids, shows slightly reduced enzyme activity |
757369 |
2.3.1.65 | BAAT-SKL |
mutant BAAT-SKL with a canonical PTS sequence has greater than a 2.5fold increase in N-acyltransferase activity compared with wild type enzyme using cholyl-CoA and taurine as substrates |
757369 |
2.3.1.65 | C235A |
activity is less than 0.4% of the wild-type activity |
659246 |
2.3.1.65 | C235S |
mutant with lower enzyme activity |
487372 |
2.3.1.65 | C235S |
mutation converts the enzyme into an efficient bile acid-CoA thioesterase |
659246 |
2.3.1.65 | C372A |
mutant with low enzyme activity |
487372 |
2.3.1.65 | D326A |
activity is less than 0.4% of the wild-type activity |
659246 |
2.3.1.65 | D328A |
inactive enzyme |
487372 |