EC Number   |
Protein Variants |
Reference |
|---|
    2.3.1.157 | A451R |
site-directed mutagenesis, neither the single mutants A451R and R439T nor the double mutant A451R/R439T affect the acetyltransferase activity significantly |
720042 |
| 2.3.1.157 | A451R/R439T |
site-directed mutagenesis, neither the single mutants A451R and R439T nor the double mutant A451R/R439T affect the acetyltransferase activity significantly |
720042 |
| 2.3.1.157 | C307S |
site-directed mutagenesis |
-, 735569 |
| 2.3.1.157 | C380A |
the acetyltransferase activity of the mutant is 2.6fold higher than that of the wild type enzyme |
-, 762386 |
| 2.3.1.157 | C380A/C405S |
the double mutant has an increased kcat/Km value compared to the wild type enzyme |
-, 762386 |
| 2.3.1.157 | C405A |
the mutant shows a slight increase in activity compared to the wild type enzyme |
-, 762386 |
| 2.3.1.157 | C405S |
the mutant has an increased kcat/Km value compared to the wild type enzyme |
-, 762386 |
| 2.3.1.157 | E458A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme, 86% of wild-type acetyltransferase activity is remaining |
719574 |
| 2.3.1.157 | H308A |
site-directed mutagenesis, the mutation diminishes both amino-sugar-1-P AcTase activities of the ST0452 protein. The mutant shows 7.7% and 0.7% of wild-type GalN-1-P AcTase and GlcN-1-P AcTase activity, respetively |
-, 729696 |
| 2.3.1.157 | H308A |
specific activity is 0.7% compared to the wild-type enzyme |
-, 729696 |
