EC Number   |
Protein Variants |
Reference |
|---|
   2.3.1.142 | A140G |
changed selectivity of acyltransferase for the 2 acetylation sites of adenylate cyclase toxin, a mixture of bi and monoacetylated toxins modified either at both Lys860 and Lys983 or only at Lys860 is generated |
486325 |
| 2.3.1.142 | A140V |
monoacetylation of adenylate cyclase toxin almost exclusively at Lys983 |
486325 |
| 2.3.1.142 | C67S |
no effect on adenylate cyclase toxin activation |
486325 |
| 2.3.1.142 | H33D |
loss of adenlayte cyclase toxin acetylation activity |
486325 |
| 2.3.1.142 | H33S |
loss of adenlayte cyclase toxin acetylation activity |
486325 |
| 2.3.1.142 | more |
construction of a fusion protein that places the 58 amino acids of Erf2 onto the C-terminus of Pfa4, another DHHC enzyme that resides in the endoplasmic reticulum membrane, the modification highly reduces the half-life of the engineered protein |
720041 |
| 2.3.1.142 | R141K |
no effect on adenylate cyclase toxin activation |
486325 |
| 2.3.1.142 | R141L |
no effect on adenylate cyclase toxin activation |
486325 |
| 2.3.1.142 | S30R |
loss of adenlayte cyclase toxin acetylation activity |
486325 |
| 2.3.1.142 | S30W |
loss of adenlayte cyclase toxin acetylation activity |
486325 |
