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EC Number
Protein Variants
Commentary
Reference
2.1.1.341
H60A
97-99% loss of activity
741347
2.1.1.341
H60A
loss of catalytic activity, mutant is able to bind both substrates
740443
2.1.1.341
M61A
97-99% loss of activity
741347
2.1.1.341
more
disruption of ligM leads to significant growth retardation on both vanillate and syringate, a ligM desA double mutant completely looses the ability to transform vanillate, phenotypes, overview
-
,
674237
2.1.1.341
R122A
97-99% loss of activity
741347
2.1.1.341
R122A/R147A
complete loss of activity
741347
2.1.1.341
Y247F
almost complete loss of activity, no discernible effect on overall protein fold or solution behavior
741347
2.1.1.341
Y247F
loss of catalytic activity, mutant is able to bind both substrates
740443
2.1.1.341
Y29A
97-99% loss of activity
741347
2.1.1.341
Y31A
97-99% loss of activity
741347
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