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Results 1 - 10 of 32 > >>
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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.169D263E severe loss of activity is due to a conflict between the catalytic His262-imidazole group and Glu-CH2 719183
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.169D263E site-directed mutagenesis, severe loss of activity is due to a conflict between the catalytic His262-imidazole group and Glu-CH2 719183
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.169D263I no activity, Ile263 can not form a H-bond with 3'-OH group 719183
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.169D263I site-directed mutagenesis, Ile263 can not form a H-bond with 3'-OH group, the mutant shows almost complete loss in activity 719183
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.169D263N site-directed mutagenesis, slight decrease in activity due to a decreased electronegativity of Asn-N compared to Asp-O, that affects charge transfer to tricetin-OH groups 719183
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.169D263N slight decrease in activity due to a decreased electronegativity of Asn-N compared to Asp-O, that affects charge transfer to tricetin-OH groups 719183
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.169E290I loss of activity is due to the fact that Ile can not form a H-bond with the 4'-OH of tricetin 719183
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.169E290I site-directed mutagenesis, almost complete loss of activity is due to the fact that Ile can not form a H-bond with the 4'-OH of tricetin 719183
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.169E290Q no activity. This mutation results in a more extensive H-bonding that hinders charge transfer and affects B-ring flexibility 719183
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.169E290Q site-directed mutagenesis, the mutation results in a more extensive H-bonding that hinders charge transfer and affects B-ring flexibility and almost complete loss in activity 719183
Results 1 - 10 of 32 > >>
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