EC Number   |
Protein Variants |
Reference |
|---|
   2.1.1.166 | D124A |
the mutant D124A is unable to rescue the growth defect of the rrmJ deletion strain, indicating that this mutation causes the inactivation of RrmJ in vivo |
704404 |
| 2.1.1.166 | D136N |
D136N mutant strain accumulates larger amounts of 30S and 50S ribosomal subunits than wild-type strains under nonstringent salt conditions, and has a significant amount of 40S ribosomal particles under stringent salt conditions |
704265 |
| 2.1.1.166 | D136N |
mutation leads to slight decrease in kcat value |
704265 |
| 2.1.1.166 | D20A |
mutation leads to slight decrease in kcat value |
704265 |
| 2.1.1.166 | D83A |
the mutant D83A is unable to rescue the growth defect of the rrmJ deletion strain, indicating that this mutation causes the inactivation of RrmJ in vivo |
704404 |
| 2.1.1.166 | E199A |
the RrmJ deletion strains expressing the E199A variant protein shows only slight growth defects, indicating that the residue is not as important in the catalytic mechanism |
704404 |
| 2.1.1.166 | F166A |
decrease in S-adenosyl-L-methionine binding affinity and/or the presence of a certain amount of an inactive yet stably folded RrmJ mutant species |
704265 |
| 2.1.1.166 | F37A/L39A |
mutant strain shows ribosome profiles that are indistinguishable from wild-type ribosome profile |
704265 |
| 2.1.1.166 | K164A |
the mutant D83A is unable to rescue the growth defect of the rrmJ deletion strain, indicating that this mutation causes the inactivation of RrmJ in vivo |
704404 |
| 2.1.1.166 | K38A |
the mutant D83A is unable to rescue the growth defect of the rrmJ deletion strain, indicating that this mutation causes the inactivation of RrmJ in vivo |
704404 |
