EC Number |
Protein Variants |
Reference |
---|
1.3.2.3 | C340A |
mutant, insensitive toward thiol oxidation, exhibits poor affinity for L-galactono-1,4-lactone |
700833 |
1.3.2.3 | C340S |
mutant, insensitive toward thiol oxidation, exhibits poor affinity for L-galactono-1,4-lactone |
700833 |
1.3.2.3 | E386A |
mutant, catalytically far less efficient than wild-type GALDH, Glu386 is involved in productive substrate binding |
697954 |
1.3.2.3 | E386D |
mutant, catalytically far less efficient than wild-type GALDH, Glu386 is involved in productive substrate binding |
697954 |
1.3.2.3 | GLDH-236OE |
homozygote mutant with enzyme overexpression |
765532 |
1.3.2.3 | L56A |
less active than the wild type enzyme |
686713 |
1.3.2.3 | L56C |
less active than the wild type enzyme |
686713 |
1.3.2.3 | L56F |
less active than the wild type enzyme |
686713 |
1.3.2.3 | L56H |
less active than the wild type enzyme and releases its FAD cofactor more easily than wild type GALDH |
686713 |
1.3.2.3 | L56I |
the mutant displays a higher turnover rate with L-galactono-1,4-lactone than the wild type enzyme |
686713 |