EC Number |
Protein Variants |
Reference |
---|
1.3.1.14 | C220A |
pyrDII mutant, conserved, essential for activity |
390928 |
1.3.1.14 | C225A |
pyrDII mutant conserved, essential for activity |
390928 |
1.3.1.14 | C228A |
pyrDII mutant conserved, essential for activity |
390928 |
1.3.1.14 | C230A |
pyrDII mutant nonconserved |
390928 |
1.3.1.14 | C243A |
pyrDII mutant conserved, essential for activity |
390928 |
1.3.1.14 | K48A |
KM-value for dihydroorotate is 2.2fold higher than wild-type value, kcat is 411fold lower than wild-type value |
674586 |
1.3.1.14 | K48E |
KM-value for dihydroorotate is 4.1fold higher than wild-type value, kcat is 67.5fold lower than wild-type value |
674586 |
1.3.1.14 | K48Q |
KM-value for dihydroorotate is 1.5fold higher than wild-type value, kcat is 448fold lower than wild-type value |
674586 |
1.3.1.14 | K48R |
KM-value for dihydroorotate is 2fold lower than wild-type value, kcat is 117fold lower than wild-type value |
674586 |