EC Number |
Protein Variants |
Reference |
---|
1.2.7.11 | C12/15A |
loss of ironĀsulfur cluster |
724470 |
1.2.7.11 | C12A |
loss of ironĀsulfur cluster. The mutant enzyme does not show formation of any radical intermediate or production of acetyl-CoA |
724470 |
1.2.7.11 | C15A |
loss of ironĀsulfur cluster. The mutant enzyme does not show formation of any radical intermediate or production of acetyl-CoA |
724470 |
1.2.7.11 | C197A |
the enzyme retains an unidentified type of ironĀsulfur cluster |
724470 |
1.2.7.11 | C46A |
loss of ironĀsulfur cluster. The mutant enzyme does not show formation of any radical intermediate or production of acetyl-CoA |
724470 |
1.2.7.11 | D468A |
inactive with 2-oxoglutarate and pyruvate as substrate |
-, 739701 |
1.2.7.11 | D468A |
mutant enzyme StOFOR1 with mutation D468A in alpha-subunit. Vmax with pyruvate as substrate is 1.3% compared to wild-type enzyme. No activity is detected with 2-oxoglutarate |
-, 739701 |
1.2.7.11 | I255L |
kcat/Km for pyruvate is 11% of wild-type value, kcat/KM for 2-oxoglutarate is 21% of wild-type value |
719399 |
1.2.7.11 | I255M |
kcat/Km for pyruvate is 13% of wild-type value, kcat/KM for 2-oxoglutarate is 2% of wild-type value |
719399 |
1.2.7.11 | I255S |
kcat/Km for pyruvate is 23% of wild-type value, kcat/KM for 2-oxoglutarate is 35% of wild-type value |
719399 |