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Results 1 - 4 of 4
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EC Number Protein Variants Commentary Reference
Show all pathways known for 1.2.1.19Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.19more a putrescine-producing recombinant Corynebacterium glutamicum strain is converted into a 4-aminobutyric acid, GABA, producing strain by heterologous expression of putrescine transaminase (PatA) and gamma-aminobutyraldehyde dehydrogenase (PatD) genes from Escherichia coli. The resultant strain produces 5.3 g/l of GABA. GABA production is improved further by adjusting the concentration of nitrogen in the culture medium, by avoiding the formation of the by-product N-acetylputrescine and by deletion of the genes for GABA catabolism and GABA re-uptake 741587
Show all pathways known for 1.2.1.19Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.19more construction of a series of Synechocystis sp. PCC6803 mutants lacking enzymes of TCAC shunt, GABA synthesis and polyamine degradation pathway, i.e. DELTAkgd, DELTAgad:DELTAkgd and DELTAgabdh encoding glutamate and 2-oxoglutarate decarboxylases, respectively. Subcloning in Escherichia coli strain DH5alpha. The level of chl a content is significantly decreased in both DELTAgabdh and DELTAgad:DELTAkgd strains as compared to that in the wild-type. Similarly, lower O2 evolution rate is observed in both mutants signifying a decline in photosynthetic efficiency, phenotype, overview. The mutant strain with disrupted gene gabdh shows an increase in gamma-aminobutyric acid (GABA), glutamate, succinate, and spermidine levels, while the DELTAgad:DELTAkgd strain shows upregulated expression of gene gadbh 763594
Show all pathways known for 1.2.1.19Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.19more generation of a ataldh10A8 T-DNA-insertion mutant that has lower levels of GABA than wild-type plants in response to salinity treatment and are more prone to salinity stress 743820
Show all pathways known for 1.2.1.19Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.19more generation of a ataldh10A9 T-DNA-insertion mutant that has lower levels of GABA than wild-type plants in response to salinity treatment and are more prone to salinity stress 743820
Results 1 - 4 of 4
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