EC Number   |
Protein Variants |
Reference |
|---|
    1.17.4.2 | C119S |
site-directed mutagenesis |
714186 |
| 1.17.4.2 | C408A |
only wild-type enzyme catalyzes epimerization of the (5'S)-[5'-2H1]- and (5'R)-[5'-2H1]-isotopomers of adenosylcobalamin, no activity of mutant enzyme |
657991 |
| 1.17.4.2 | C408S |
only wild-type enzyme catalyzes epimerization of the (5'S)-[5'-2H1]- and (5'R)-[5'-2H1]-isotopomers of adenosylcobalamin, no activity of mutant enzyme |
657991 |
| 1.17.4.2 | C644A |
mutant enzyme is devoid of significant activity |
-, 660352 |
| 1.17.4.2 | C647A |
mutant enzyme displays 2% of wild-type activity |
-, 660352 |
| 1.17.4.2 | C662A |
mutant enzyme is devoid of significant activity |
-, 660352 |
| 1.17.4.2 | C665A |
mutant enzyme is devoid of significant activity |
-, 660352 |
| 1.17.4.2 | more |
cell lacking thioredoxins exhibit an elongated S phase and accumulate subunit R1 in its oxidized form. Cells also contain significantly decreased deoxyribonucleotide levels during the S phase. Overexpressing subunit R1 in these cells increases both the amount of R1 reduced form and the concentrations of deoxyribonucleotides and accelerates DNA replication |
673802 |
| 1.17.4.2 | more |
construction of two T-DNA insertion mutants of the RNR2Tso2, inserted within the coding sequence of the second exon of RNR2Tso2. No plants homozygous for the T-DNA allele are detectable for either allele |
-, 716563 |
| 1.17.4.2 | more |
fnr and arcA mutant strains are constructed by introducing the indicated mutation into strain IG40 by P1 transduction followed by selection for the appropriate drug resistance |
687196 |
