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EC Number Protein Variants Commentary Reference
Show all pathways known for 1.14.19.20Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.20G111R naturally occurring mutation, the mutant is obtained from a patient with prosthetic valve endocarditis, the mutant shows reduction in sterol desaturase activity and resistance to azole and echinocandin antifungals, replacement of both mutant alleles in the resistant isolate with the susceptible isolate's allele restores wild-type susceptibility to all azoles and echinocandins tested. -, 744054
Show all pathways known for 1.14.19.20Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.20G234A inactive mutant enzyme 390939
Show all pathways known for 1.14.19.20Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.20G234A no activity 390939
Show all pathways known for 1.14.19.20Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.20G234D 2% of wild-type activity 390939
Show all pathways known for 1.14.19.20Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.20G234D low activity 390939
Show all pathways known for 1.14.19.20Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.20H147E inactive mutant enzyme 390939
Show all pathways known for 1.14.19.20Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.20H147E no activity 390939
Show all pathways known for 1.14.19.20Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.20H147L inactive mutant enzyme 390939
Show all pathways known for 1.14.19.20Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.20H147L no activity 390939
Show all pathways known for 1.14.19.20Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.20H151E inactive mutant enzyme 390939
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