EC Number   |
Protein Variants |
Reference |
|---|
    1.14.15.18 | G125E |
native mutant, no enzyme activity but normal expression level |
440126 |
| 1.14.15.18 | more |
construction and expression in COS cell line of a chimeric fusion protein: vitaminD receptor ligand-binding domain with the yeast GAL4 DNA-binding domain, also expression of lacZ containing reporter plasmid |
440125 |
| 1.14.15.18 | more |
construction of 25-hydroxyvitamin D-1alpha-hydroxylase and PTH double knockout mice, NH2-terminal fragments of PTH and PTH-related protein, PTHrP, on the skeleton of young mutant mice is an increase in both endochondral bone and appositional formation without increased bone resorption, phenotype, overview, PTH is the major protein hormone regulating calcium homeostasis, PTHrP is a PTH-like factor responsible for humoral hypercalcemia of malignancy, both peptides are required to achieve normal fetal skeletal morphogenesis |
674990 |
| 1.14.15.18 | more |
construction of a transgenic mouse line expressing 1501 bp of 58 flanking region together with 44 bp of 58 untranslated region of the human CYP27B1 gene fused to the firefly luciferase reporter gene, luciferase protein and mRNA for CYP27B1 are localized to proximal convoluted tubule cells of the kidney with highest levels in 2-week-old animals, overview |
675474 |
| 1.14.15.18 | more |
expression of vitamin D hydroxylases in the VDR-/- mouse model, overview |
672936 |
| 1.14.15.18 | P382S |
native mutant, no enzyme activity but normal expression level |
440126 |
| 1.14.15.18 | Q65A |
site-directed mutagenesis, three-dimensional structure analysis and comparison to the wild-type enzyme |
674468 |
| 1.14.15.18 | Q65E |
site-directed mutagenesis, three-dimensional structure analysis and comparison to the wild-type enzyme |
674468 |
| 1.14.15.18 | Q65H |
site-directed mutagenesis, three-dimensional structure analysis and comparison to the wild-type enzyme |
674468 |
| 1.14.15.18 | Q65L |
site-directed mutagenesis, three-dimensional structure analysis and comparison to the wild-type enzyme |
674468 |
