EC Number   |
Protein Variants |
Reference |
|---|
   1.14.14.B11 | C330W |
inactive |
728555 |
| 1.14.14.B11 | C330W |
isoform CYP82E3 variant, active |
687594 |
| 1.14.14.B11 | E375K |
loss of catalytic activity |
689241 |
| 1.14.14.B11 | K269N |
isoform CYP82E3 variant, no catalytic activity |
687594 |
| 1.14.14.B11 | K269N/I274Null |
isoform CYP82E3 variant, no catalytic activity |
687594 |
| 1.14.14.B11 | K269N/I274Null/T279A |
isoform CYP82E3 variant, no catalytic activity |
687594 |
| 1.14.14.B11 | more |
analysis of polymorphic variations of the CYP82E2 orthologs in Nicotiana sylvestris and various Nicotiana tabacum genotypes |
689241 |
| 1.14.14.B11 | more |
enzyme silencing by CYP82E21-specific RNAi expression. CYP82E4v1-interference affects the accumulation of nicotine and nornicotine, and the RNAi vector for CYP82E4v1 effectively silences CYP82E4v1 expression and further blocks the synthesis of nornicotine |
746124 |
| 1.14.14.B11 | more |
enzyme silencing by introducing a CYP82E21-specific RNAi construct in ovaries, silencing of CYP82E21 leads to up to 90% reduced nicotine conversion in flower ovaries |
746003 |
| 1.14.14.B11 | more |
inhibition of gene expression by RNAi leads to up ot sixfold decrease in nornicotine content with concomitant decrease in N'-nitrosonornicotine and total tobacco-specific nitrosamines |
689456 |
