1.14.14.113 | more |
metabolic engineering: functional co-expression of a gene cluster encoding four enzymes of the mevalonate pathway, i.e. mevalonate kinase, phosphomevalonate kinase, mevalonate diphosphate decarboxylase, and isopentenyl diphosphate isomerase, with CYP71BA1 and ZSS1, encoding alpha-humulene synthase, in Escherichia coli leading to the production of 10-hydroxy-alpha-humulene in the presence of mevalonate, overview |
717468 |