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EC Number
Protein Variants
Commentary
Reference
1.1.1.269
K160A
inactive
711235
1.1.1.269
K214A
substantially reduced catalytic efficiencies with the natural substrates in both the oxidative and reductive direction
711235
1.1.1.269
R211A
substantially reduced catalytic efficiencies with the natural substrates in both the oxidative and reductive direction
711235
1.1.1.269
S143A
residue acts as H-bond donor to substrate and in charge stabilization of the transition state, large increase in Km value
711235
1.1.1.269
Y156A
mutation in general acid/base, large increase in Km value
711235
1.1.1.269
Y156F
inactive
711235
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