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EC Number
Protein Variants
Commentary
Reference
1.1.1.170
A94T
naturally occurring missense mutant, mutant is not able to complement erg26 deficiency in Saccharomyces cerevisiae strain SDG200
656813
1.1.1.170
G280A
loss of a HhaI restriction site
656813
1.1.1.170
Gly90Ser
naturally occuring mutation of ERG26 that confers resistance to inhibitor FR171456
-
,
741051
1.1.1.170
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multiple mutations in ERG26 confer resistance to inhibitor FR171456 in growth and enzyme assays. Some of these ERG26 mutations likely alter Erg26 binding to FR171456, based on a structure model of Erg26
-
,
741051
1.1.1.170
V53D
naturally occurring missense mutant, mutant is not able to complement erg26 deficiency in Saccharomyces cerevisiae strain SDG200
656813
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