EC Number |
Protein Variants |
Reference |
---|
6.5.1.3 | D292E |
about 10% of the ligation activity of wild-type enzyme |
662241 |
6.5.1.3 | E296A |
about 10% of the ligation activity of wild-type enzyme |
662241 |
6.5.1.3 | Y5A |
about 10% of the RNA ligation activity of wild-type enzyme, mutant enzyme displays 39% of the adenylyltransferase activity observed with wild-type enzyme |
662241 |
6.5.1.3 | K54A |
about 15% of the RNA ligation activity of wild-type enzyme, mutant displays near wild-type adenylyltransferase activity |
662241 |
6.5.1.3 | Q106A |
about 20% of the RNA ligation activity of wild-type enzyme, mutant displays near wild-type adenylyltransferase activity |
662241 |
6.5.1.3 | S292N |
about 25% of the ligation activity of wild-type enzyme |
662241 |
6.5.1.3 | R155A |
about 35% of the ligation activity of wild-type enzyme, mutant enzyme displays 16% of the adenylyltransferase activity observed with wild-type enzyme |
662241 |
6.5.1.3 | D135A |
about 5% of the ligation activity of wild-type enzyme, mutant enzyme displays 4% of the adenylyltransferase activity observed with wild-type enzyme |
662241 |
6.5.1.3 | S170A |
about 5% of the ligation activity of wild-type enzyme, mutant enzyme displays 8% of the adenylyltransferase activity observed with wild-type enzyme |
662241 |
6.5.1.3 | E300A |
about 50% of the ligation activity of wild-type enzyme |
662241 |