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Results 1 - 9 of 9
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EC Number Protein Variants Commentary Reference
Display the reaction diagram Show all sequences 6.2.1.76H206L kcat value for malonyl-CoA formation is reduced 40fold 764096
Display the reaction diagram Show all sequences 6.2.1.76K170M kcat value for malonyl-CoA formation is reduced 2.2fold 764096
Display the reaction diagram Show all sequences 6.2.1.76K170M mutant enzyme retains 35% of its activity 765732
Display the reaction diagram Show all sequences 6.2.1.76R168G kcat value for malonyl-CoA formation is reduced 1.7fold. The mutant enzyme shows slightly higher methyl malonyl-CoA synthetase activity than the wild type 764096
Display the reaction diagram Show all sequences 6.2.1.76R168G mutation reduces 63% of enzyme activity 765732
Display the reaction diagram Show all sequences 6.2.1.76R168G/K170M kcat value for malonyl-CoA formation is reduced 6.1fold 764096
Display the reaction diagram Show all sequences 6.2.1.76R168G/K170M the mutant enzyme retains 12% of its activity 765732
Display the reaction diagram Show all sequences 6.2.1.76R354A the mutant enzyme is completely devoid of malonyl-CoA synthetase activity, although the Ala354 mutant retains the same very low activity toward acetate that is observed with the wild-type enzyme 765038
Display the reaction diagram Show all sequences 6.2.1.76R354L the mutant enzyme is completely devoid of malonyl-CoA synthetase activity 765038
Results 1 - 9 of 9
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